Which combination of tests might be ordered for proliferative diabetic retinopathy?

• A. OCT and topo
• B. OCT and FA
• C. Fundus and pachy
• D. OCT of cornea and pachy

Answer: (B)

In proliferative diabetic retinopathy, you need imaging that shows both the retina’s structure and its vasculature to guide treatment. OCT gives cross-sectional detail of the retina, so you can assess macular edema, retinal thickness, and any tractional membranes that might develop. Fluorescein angiography maps the retinal blood vessels, revealing active neovascularization and areas of nonperfusion that drive proliferative changes and indicate where laser treatment or anti-VEGF therapy is needed.

Together, OCT and fluorescein angiography provide complementary information: OCT shows the tissue architecture and edema, while FA identifies abnormal vessels and perfusion deficits. The other options include tests focused on areas like the cornea or non-retinal measurements, which don’t supply the essential vascular imaging or retinal structural detail needed for managing proliferative disease.